Dr. Sylvester Willard was accepted into the Cayuga County Medical Society in 1824 and practiced in the area until the 1830s. After spending several years away, he returned in 1843 and purchased the house that is now the Cayuga Museum. Dr. Willard added the east wing to the mansion in the 1850s to create an in-home medical office, and in the 1870s installed a Tiffany stained glass window. He also added a separate entrance in this wing so patients could enter directly into the office rather than going through the house. 

The objects on display come from a collection of medical equipment from the Cayuga County Medical Society and include a look in to 19th Century medicine, the medical experience of women at the time, a surgical table, medical tools from the time period, and much more.